WNT1-inducible-signaling pathway protein 2; WISP-2; connective tissue growth factor-like protein; CTGF-L; connective tissue growth factor-related protein 58 (WISP2, CCN5, CT58, CTGFL, UNQ228/PRO261)

Function

• may play an important role in modulating bone turnover
• promotes adhesion of osteoblast cells & inhibits binding of fibrinogen to integrin receptors
• inhibits osteocalcin production Structure:
• belongs to the CCN family
• contains 1 IGFBP N-terminal domain
• contains 1 TSP type-1 domain
• contains 1 VWFC domain Compartment: secreted (probable) Expression:
• expressed in primary osteoblasts, fibroblasts, ovary, testes, & heart

More general terms

• WNT1 inducible signaling pathway protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8839
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8839
• OMIM: https://mirror.omim.org/entry/603399
• UniProt: http://www.uniprot.org/uniprot/O76076.html