postmeiotic segregation increased 2-like protein 1; postmeiotic segregation increased 2-like protein 6; postmeiotic segregation increased 2-like protein 13; postmeiotic segregation increased protein 3; hPMS3; postmeiotic segregation increased protein 8 (PMS2L1, PMS2P1, PMS2L13, PMS2L6, PMS3, PMS8)

Structure

• belongs to the DNA mismatch repair mutL/hexB family
• contains 1 histidine kinase domain

Alternative splicing

named isoforms=2

Expression

• highly expressed in kidney, spleen, adrenal gland, ovary & cerebellum & to a lower extent in liver, esophagus, stomach, duodenum, colon, bladder, uterus, lung, pancreas & cerebrum
• not expressed in heart

Genetics

• encoded by one of the numerous copies of postmeiotic segregation increased 2-like genes scattered in the q11-q22 region of the chromosome 7

More general terms

• mutL/PMS1 family protein

Database

• OMIM: https://mirror.omim.org/entry/605038
• UniProt: http://www.uniprot.org/uniprot/A4D2B8.html