WD repeat-containing protein 9; bromodomain & WD repeat-containing protein 1 (BRWD1, C21orf107, WDR9)

Function

• may be a transcriptional activator
• may be involved in chromatin remodeling (putative)
• phosphorylated upon DNA damage, probably by ATM or ATR
• interacts with SMARCA4 (putative)

Structure

• contains 2 bromo domains
• contains 8 WD repeats

Compartment

cytoplasm. nucleus (putative)

Alternative splicing

named isoforms=3; A,B,C

Expression

ubiquitously expressed

More general terms

• WD repeat protein family
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54014
• UniProt: http://www.uniprot.org/uniprot/Q9NSI6.html