tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; tyrosine-protein kinase DTK; tyrosine-protein kinase byk (TYRO3, BYK, DTK, RSE, SKY)

Function

• may be involved in cell adhesion processes, especially in the central nervous system

Structure

• monomer & homodimer
• interacts with GAS6
• belongs to the protein kinase superfamily, Tyr protein kinase family, AXL/UFO subfamily
• contains 2 fibronectin F3 modules
• contains 2 Ig-like C2-type domains (immunoglobulin-like)
• contains 1 protein kinase domain

Compartment

cell membrane

Expression

• abundant in the brain
• lower levels in other tissues

Pathology

• cell entry factor in ilovirus infection (putative)

More general terms

• tyrosine kinase receptor (RTK)

Additional terms

• tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; tyrosine-protein kinase DTK; tyrosine-protein kinase byk (TYRO3, BYK, DTK, RSE, SKY)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7301
• OMIM: https://mirror.omim.org/entry/600341
• UniProt: http://www.uniprot.org/uniprot/Q06418.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7301