sperm 1 POU domain transcription factor; SPRM-1 (SPRM1, POU5F2)

Function

• transcription factor
• binds preferentially to the octamer motif (5'-ATGTTAAT-3')
• may exert a regulatory function in meiotic events required for terminal differentiation of male germ cell

Structure

• belongs to the POU transcription factor family, class-5 subfamily
• contains 1 homeobox DNA-binding domain
• contains 1 POU-specific domain

Compartment

nucleus

More general terms

• homeobox protein
• POU protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N7G0.html