GS homeobox 1; homeobox protein GSH-1 (GSX1, GSH1)

Function

• probable transcription factor
• binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'
• activates transcription of the GHRH gene
• role in pituitary development

Structure

• belongs to the antp homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (putative)

More general terms

• homeobox protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=219409
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:219409
• UniProt: http://www.uniprot.org/uniprot/Q9H4S2.html