sorting nexin-17 (SNX17 KIAA0064)

Function

• may be involved in protein trafficking
• interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 & LRP8

Structure

• the PX domain is required for association with endosomes
• belongs to the sorting nexin family
• contains 1 PX (phox homology) domain
• contains 1 Ras-associating domain

Compartment

• cytoplasm. early endosome
• associated with early endosomes

More general terms

• sorting nexin
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9784
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9784
• OMIM: https://mirror.omim.org/entry/605963
• UniProt: http://www.uniprot.org/uniprot/Q15036.html