6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (6PF-2-K/Fru-2,6-Pase)

Function

• dual function phosphomonoesterase

ATP + D-fructose 6-phosphate -> ADP + D-fructose 2,6-bisphosphate

D-fructose 2,6-bisphosphate + H2O -> D-fructose 6-phosphate + phosphate

More general terms

• phosphofructokinase
• phosphomonoesterase

More specific terms

• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1; 6PF-2-K/fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/fru-2,6-P2ase liver isozyme; includes: 6-phosphofructo-2-kinase; fructose-2,6-bisphosphatase (PFKFB1, F6PK PFRX)
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6PF-2-K/fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/fru-2,6-P2ase heart-type isozyme; includes: 6-phosphofructo-2-kinase; fructose-2,6-bisphosphatase (PFKFB2)
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; 6PF-2-K/fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/fru-2,6-P2ase brain/placenta-type isozyme; renal carcinoma antigen NY-REN-56; iPFK-2; includes: 6-phosphofructo-2-kinase; fructose-2,6-bisphosphatase ...
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4; 6PF-2-K/fru-2,6-P2ase 4; PFK/FBPase 4; 6PF-2-K/fru-2,6-P2ase testis-type isozyme; includes: 6-phosphofructo-2-kinase; fructose-2,6-bisphosphatase (PFKFB4)