zinc finger protein 467 (ZNF467)

Function

• transcriptional regulation
• binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE)
• transactivates several promoters including FOS & OSM
• interacts with STAT3; enhances STAT3 activity by keeping it in the nucleus

Structure

• belongs to the krueppel C2H2-type zinc-finger protein family
• contains 12 C2H2-type zinc fingers

Compartment

nucleus

More general terms

• C2H2 type zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=168544
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:168544
• OMIM: https://mirror.omim.org/entry/614040
• UniProt: http://www.uniprot.org/uniprot/Q7Z7K2.html