general transcription factor IIF subunit 2; ATP-dependent helicase GTF2F2; general transcription factor IIF 30 kD subunit; transcription initiation factor IIF subunit beta; TFIIF-beta; transcription initiation factor RAP30 (GTF2F2, RAP30)

Function

• small subunit of TFIIF
• RNA Polymerase 2 recruitment activity resides in small subunit of TFIIF
• has ATP-dependent DNA-helicase activity
• interacts with HTATSF1 & GPBP1 (putative)
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the TFIIF beta subunit family

Compartment

nucleus

More general terms

• transcription factor IIF subunit
• phosphoprotein
• helicase (DNA unwinding protein, DNA untwisting protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2963
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2963
• OMIM: https://mirror.omim.org/entry/189969
• UniProt: http://www.uniprot.org/uniprot/P13984.html