transcription initiation factor IIA beta (TFIIA p19 subunit)
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Function
- TFIIA-alpha & TFIIA-beta derived from same gene transcript
- alpha & beta subunits are postranslationally produced from the precursor form by TASP1
- the cleavage promotes proteosomal degradation
Structure
- TFIIA is a heterodimer of the large unprocessed subunit 1 & a small subunit gamma
- originally believed to be a heterotrimer of an alpha (p35), a beta (p19) & a gamma subunit (p12)