threonine aspartase 1 (Taspase-1, [Contains: Threonine aspartase subunit alpha; Threonine aspartase subunit beta], TASP1, C20orf13)

Function

• protease involved in MLL processing
• expression of early HOXA gene cluster
• intramolecular proteolysis generates 2 subunits, alpha & beta, which association (non-covalently) to form active enzyme

Structure

• belongs to the asparaginase 2 family

More general terms

• protease; proteinase; endopeptidase

Database

• OMIM: https://mirror.omim.org/entry/608270
• UniProt: http://www.uniprot.org/uniprot/Q9H6P5.html