cytoplasmic dynein 2 heavy chain 1; cytoplasmic dynein 2 heavy chain; dynein cytoplasmic heavy chain 2; dynein heavy chain isotype 1B; dynein heavy chain 11; hDHC11 (DYNC2H1, DHC1B, DHC2, DNCH2, DYH1B, KIAA1997)
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Function
- component of cytoplasmic dynein complex 2
- motor for intraflagellar retrograde transport (putative)
- cilia biogenesis
- role in transport between endoplasmic reticulum & Golgi or organization of the Golgi in cells (putative)
Structure
- belongs to the dynein heavy chain family
Compartment
- cell projection, cilium axoneme; peripheral membrane
- cytoplasm
- localizes to the apical cytoplasm
- localizes to Golgi apparatus, cytoplasmic vesicle & endoplasmic reticulum[2]
Alternative splicing
named isoforms=3
More general terms
Additional terms
Component of
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q8NCM8.html
- ↑ 2.0 2.1 Vaisberg EA, Grissom PM, McIntosh JR. Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles. J Cell Biol. 1996 May;133(4):831-42. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8666668