dynein heavy chain 11; ciliary dynein heavy chain 11; axonemal dynein heavy chain 11 (DNAH11)

Function

• dynein heavy chain
• force generating protein of respiratory cilia

Structure

• belongs to the dynein heavy chain family (see dynein heavy chain)

Pathology

• defects in DNAH11 are a cause of:
  • situs inversus viscerum
  • primary ciliary dyskinesia

More general terms

• dynein heavy chain

Additional terms

• cytoplasmic dynein 2 heavy chain 1; cytoplasmic dynein 2 heavy chain; dynein cytoplasmic heavy chain 2; dynein heavy chain isotype 1B; dynein heavy chain 11; hDHC11 (DYNC2H1, DHC1B, DHC2, DNCH2, DYH1B, KIAA1997)
• dynein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8701
• OMIM: https://mirror.omim.org/entry/242650
• OMIM: https://mirror.omim.org/entry/270100
• OMIM: https://mirror.omim.org/entry/603339
• UniProt: http://www.uniprot.org/uniprot/Q96DT5.html