somatostatin receptor 5; SS5R (SSTR5)

Function

• receptor for somatostatin-28 & to a lesser extent for somatostatin-14.
• activity is mediated by G proteins which inhibit adenylyl cyclase

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• adult pituitary gland, heart, small intestine, adrenal gland, cerebellum
• expressed in fetal hypothalamus
• no expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary

More general terms

• somatostatin receptor
• phosphoprotein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6755
• OMIM: https://mirror.omim.org/entry/182455
• UniProt: http://www.uniprot.org/uniprot/P35346.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6755