intrinsic urethral sphincter deficiency (ISD)

Etiology

• congenital sphincter weakness
  • myelomeningocele
  • epispadias
• acquired subsequent to:
  • prostatectomy,
  • trauma
  • radiation therapy
  • sacral spinal cord lesions

Pathology

• urethral sphincter is unable to contract & generate sufficient resistance in the bladder, especially during stress maneuvers, resulting in stress urinary incontinence

Clinical manifestations

• stress urinary incontinence

More general terms

• urethral disorder

Additional terms

• stress urinary incontinence