ephrin type-A receptor 1; tyrosine-protein kinase receptor EPH (EPHA1, EPH, EPHT, EPHT1)

Function

• receptor for members of the ephrin-A family
• binds with a low affinity to ephrin-A1

Structure

• belongs to the protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
• contains 2 fibronectin F3 modules
• contains 1 protein kinase domain
• contains 1 SAM (sterile alpha motif) domain

Compartment

membrane

Pathology

overexpressed in several carcinomas

More general terms

• ephA receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2041
• OMIM: https://mirror.omim.org/entry/179610
• UniProt: http://www.uniprot.org/uniprot/P21709.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2041