tripartite motif-containing protein 29; ataxia telangiectasia group D-associated protein (TRIM29, ATDC)

Function

• able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line
• constitutively phosphorylated by PKC on Ser/Thr in A431 cells
• interacts with VIM & HINT1

Structure

contains 1 B box-type Zn+2 finger

Compartment

• cytoplasm
• colocalizes with intermediate filaments

Alternative splicing

named isoforms=2; alpha, beta

Expression

expressed in placenta, prostate & thymus

More general terms

• tripartite motif-containing protein (trim protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23650
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23650
• OMIM: https://mirror.omim.org/entry/610658
• UniProt: http://www.uniprot.org/uniprot/Q14134.html