phosphodiesterase 6; rhodopsin-sensitive cGMP-specific phosphodiesterase (PDE6)

Expression

• present in retina

Pharmacology

• inhibited by sildenafil (Viagra) resulting in visual disturbances

More general terms

• cyclic nucleotide phosphodiesterase

More specific terms

• cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'; cGMP phosphodiesterase 6C (PDE6Cc, PDEA2)
• photoreceptor cGMP phosphodiesterase
• retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; GMP-PDE gamma (PDE6H)
• retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; GMP-PDE delta; protein p17 (PDE6D, PDED)
• retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; GMP-PDE gamma (PDE6G, PDEG)
• Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; GMP-PDE alpha; PDE V-B1 (PDE6A, PDEA)
• Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; GMP-PDE beta (PDE6B, PDEB)

Additional terms

• sildenafil (Viagra, Revatio, Caverta)