diabetic polyneuropathy
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Introduction
Epidemiology
- most common form of polyneuropathy
Pathology
- longest nerves are affected most severely
- small & large sensory fiber affected
- distal motor fibers less affected[1]
Clinical manifestations
- symptoms generally begin in the feet, then ascend up to legs
- later affects hands in stocking-glove distribution
Laboratory
Management
- glycemic control
- management of modifiable risk factors
- exercise
- management of dyslipidemia
- management of weight, obesity
- frequent foot exams
- antidepressants
- anticonvulsants
- capsaicin topical