hand-foot-&-mouth disease
Jump to navigation
Jump to search
Etiology
Epidemiology
- summer & fall
- primarily in children < 10 years of age
- multiple family members affected
- enterovirus 71 cause of epidemic deaths (~54 children) in Camdodia 2012
- also reported in military trainees[6]
- case report in an adult[7]
Clinical manifestations
- tender vesicles, erosions in mouth
- can occur in the absence of oral lesions[6]
- 0.25 cm papules on hands & feet with rim of erythema (erythematous halo) evolving into tender vesicles
- occurrence of a varicella-like rash or a rash with an atypical distribution may represent an atypical presentation[5]
- transient fever
- spontaneous resolution in 100% of those affected in military outbreak[6]
- case report in adult[7]
- lesions on the palms resolved within 2 weeks
- lesions on the feet & on the oral mucosa resolved within 8 weeks[7]
* images of infection in an adult[7]
More general terms
Additional terms
References
- ↑ Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 317-18
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 93
- ↑ 3.0 3.1 Severe Complications of hand, foot and mouth disease (HFMD) caused ny EV-71 in Cambodia - conclusion of joint investigation World Health Organization http://www.who.int/csr/don/2012_07_13/en/index.html
- ↑ Centers for Disease Control and Prevention Notes from the Field: Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 2011-February 2012 MMWR March 30, 2012 / 61(12);213-214 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6112a5.htm
- ↑ 5.0 5.1 Buttery VW et al Notes from the Field: Atypical Presentations of Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 - Minnesota, 2014. MMWR Weekly. July 31, 2015 / 64(29);805 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6429a8.htm
- ↑ 6.0 6.1 6.2 6.3 6.4 Banta J, Lenz B, Pawlak M et al. Notes from the Field: Outbreak of hand, foot, and mouth disease caused by coxsackievirus A6 among basic military trainees - Texas, 2015. MMWR Morb Mortal Wkly Rep 2016 Jul 8; 65:678. http://www.cdc.gov/mmwr/volumes/65/wr/mm6526a3.htm
- ↑ 7.0 7.1 7.2 7.3 7.4 Murase C, Akiyama M Hand, Foot, and Mouth Disease in an Adult. N Engl J Med 2018; 378:e20. April 5, 2018 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29617579 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMicm1713548
- ↑ A Guide to Clinical Management and Public Health Response for Hand, Foot and Mouth Disease (HFMD) World Health Organization http://www.wpro.who.int/publications/docs/GuidancefortheclinicalmanagementofHFMD.pdf
- ↑ Centers for Disease Control and Prevention Hand, Foot, and Mouth Disease (HFMD) http://www.cdc.gov/hand-foot-mouth/about/index.html