crush syndrome

Introduction

Shock & renal failure following soft tissue injury.

Etiology

• rhabdomyolysis

Clinical manifestations

• signs of injury
• shock
• oliguria
• pain
• somnolence
• thirst
• nausea

Laboratory

• increased serum markers of muscle injury
  • serum creatine kinase*
  • serum myoglobin
• increased serum urea nitrogen
• serum K+: hyperkalemia
• serum Na+: hyponatremia
• urine myoglobin: myoglobinuria*

* serum creatinine kinase (> 5x upper limit of normal) for diagnosis

* urine myoglobin for management (see rhabdomyolysis)

More general terms

• syndrome