pyogenic granuloma ;granuloma telangiectaticum; lobular capillary hemangioma
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Introduction
A rapidly developing hemangioma occasionally occurring at sites of minor trauma.
Etiology
Epidemiology
- children & adults < 30 years old
- no sex predilection
Pathology
- proliferation of capillaries
- prominent endothelial cells within edematous, gelatinous stroma
- epidermis is commonly eroded
- dense infiltrate of neutrophils is common
* histopathology image[6]
Clinical manifestations
- solitary erodied vascular nodule that bleeds spontaneously or following minor trauma
- bright red, dusky red, violaceous or brown-black nodule with smooth surface < 1.5 cm in diameter
- dome-shaped, sessile or pedunculated
- occurs as solitary lesion on finger, lip, mouth, trunk or toe
- may be epidermal collarette at base on palm or sole
- lesions may persist for months
Laboratory
- biopsy with histological examination
Differential diagnosis
- nodular malignant melanoma (may be amelanotic)[6]
- squamous cell carcinoma
- glomus tumor
- nodular basal cell carcinoma
- metastatic carcinoma
- bacillary angiomatosis
Management
- biopsy with histological examination
- surgical excision (recurrence uncommon)
- curettage of scissor excision (for histopathology) followed by electrodessication or pulse dye laser (lesions may recur)
More general terms
References
- ↑ Color Atlas & Synopsis of Clinical Dermatology, Common & Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 160-61
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
- ↑ 3.0 3.1 Pierson JC, James WD (images) Dermatologic Manifestations of Pyogenic Granuloma (Lobular Capillary Hemangioma). http://emedicine.medscape.com/article/1084701-overview
- ↑ 4.0 4.1 DermNet NZ. Pyogenic granuloma (images) http://www.dermnetnz.org/vascular/pyogenic-granuloma.html
- ↑ 5.0 5.1 NEJM Knowledge+ Question of the Week. Aug 22, 2017 https://knowledgeplus.nejm.org/question-of-week/1424/
- ↑ 6.0 6.1 6.2 6.3 Lipner SR Ulcerated Nodule of the Fingernail. JAMA. Published online February 16, 2018. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29453865 https://jamanetwork.com/journals/jama/fullarticle/2672333