cavernous sinus thrombosis
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Introduction
also see cerebral vein thrombosis
Etiology
- contiguous spread of infection from sinus infection, dental infection
- Staphylococcus aureus in 70%[3]
Pathology
- thrombosis of the cavernous sinus(es)
- involvement of cranial nerve 3, cranial nerve 4 & cranial nerve 6
Clinical manifestations
- ptosis
- chemosis
- painful ophthalmoplegia
- retro-orbital throbbing headache
- periorbital edema
- diplopia
- ocular paralysis
- facial numbness., cranial nerve 5 palsy[4]
- partial Horner's syndrome[4]
Laboratory
Diagnostic procedures
- lumbar puncture with CSF analysis (exclude meningitis)
Radiology
- MRI neuroimaging[3]
- magnetic resonance venography may be helpful
Management
- life threatening
- antibiotic coverage for Staphylococcus aureus
- neurosurgical drainage
More general terms
Additional terms
References
- ↑ Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004
- ↑ Pikija S, Mutzenbach JS Septic Cerebral Venous Thrombosis. N Engl J Med 2015; 373:1553. October 15, 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26465988 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMicm1415937
- ↑ 3.0 3.1 3.2 Medical Knowledge Self Assessment Program (MKSAP) 18, 19. American College of Physicians, Philadelphia 2018, 2021
- ↑ 4.0 4.1 4.2 4.3 NEJM Knowledge+ Question of the Week Feb 18, 2020 https://knowledgeplus.nejm.org/question-of-week/1356/