Kluver-Bucy syndrome
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Introduction
1st described in 1975 in a patient with herpes encephalitis.
Etiology
- herpes encephalitis
- Pick's disease
- Alzheimer's disease
- cerebral trauma
- stroke
- temporal lobe epilepsy
- Huntington's chorea
- hypoxia
- hypoglycemia
- subarachnoid hemorrhage
- neuroleptics
- heat stroke
Pathology
- bilateral temporal lobe dysfunction
Clinical manifestations
- psychic blindness (monkeys)
- hyper-reactivity to visual stimuli
- visual agnosia
- increased oral & sexual activity
- depressed drive & emotional reactions
- other manifestations that may occur
Management
- symptomatic & supportive
- medroxyprogesterone[3]
- androgen deprivation therapy[3]
- SSRI may be helpful, but not 1st line[3]
- prognosis
- no cure, but not life-threatening
- patient can be difficult to manage
- symptoms may slowly decline with treatment
More general terms
References
- ↑ Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
- ↑ Lilly R et al, Neurology 33:1141, 1983
- ↑ 3.0 3.1 3.2 3.3 Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
- ↑ NINDS Kluver-Bucy Syndrome Information Page https://www.ninds.nih.gov/disorders/all-disorders/kl%C3%BCver-bucy-syndrome-information-page