vulvar intraepithelial hyperplasia

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Introduction

Dysplastic or neoplastic changes in the vulvar squamous epithelium.

Epidemiology

Clinical manifestations

Laboratory

  • biopsy confirms diagnosis

Management

  • wide local excision
  • imiquimod 5% often effective in HPV-positive women
  • prognosis: rarely a precursor to invasive disease

More general terms

References

  1. 1.0 1.1 Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004
    Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
    Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
    Geriatric Review Syllabus, 9th edition (GRS9) Medinal-Walpole A, Pacala JT, Porter JF (eds) American Geriatrics Society, 2016
  2. 2.0 2.1 Geriatrics at your Fingertips, 13th edition, 2011 Reuben DB et al (eds) American Geriatric Society
  3. ACOG Committee Opinion No. 509: Management of vulvar intraepithelial neoplasia. Obstet Gynecol. 2011 Nov;118(5):1192-4 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22015906