diagnostic criteria for frontotemporal dementia
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Introduction
Essential features:
- insidious onset & gradual progression
- early decline in social interpersonal conduct
- early impairment in regulation of personal conduct
- early emotional blunting
- early loss of insight
Supportive features:
- behavior
- decline in personal hygiene & grooming
- mental rigidity & inflexibility
- distractability & impersistence
- hyperoral behavior & dietary changes
- perseveration & stereotypy
- speech & language
- signs
- primitive reflexes (frontal release signs)
- incontinence
- akinesia, rigidity & tremor
- low & labile blood pressure
- neuropsychiatric testing
- impairment on frontal lobe tests
- absence of:
- normal conventional EEG despite dementia
- MRI or PET show predominant frontal lobe &/or anterior temporal lobe abnormality
- onset before age 65
- positive family history in a 1st degree relative
- associated motor neuron disease (minority of patients)
Notes
More general terms
Additional terms
References
- ↑ Cummings JL, The Neuropsychiatry of Alzheimer's Disease and Related Dementias, Martin Dunitz, 2003
- ↑ Piguet O et al. Sensitivity of current criteria for the diagnosis of behavioral variant frontotemporal dementia. Neurology 2009 Feb 24; 72:732. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19237702
- ↑ 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015