advanced sleep-phase syndrome; familial advanced sleep-phase syndrome (FASPS)

^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

Epidemiology

common in the elderly

persistent early onset of sleep (8-9 PM)
early morning awakening (3-5 AM)
individuals are 'morning larks' with a 4 hours advance of the sleep, temperature & melatonin rhythms

improved sleep hygiene may be beneficial
- systematic gradual advancement of bedtime
- bright light therapy early in the evening
  - typical indoor lighting is inadequate
  - sunlight or commercially available light box is needed

↑ UniProt http://www.uniprot.org/uniprot/P48730.html
↑ OMIM https://mirror.omim.org/entry/604348
↑ UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
↑ Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
↑ Barion A, Zee PC. A clinical approach to circadian rhythm sleep disorders. Sleep Med. 2007 Sep;8(6):566-77 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17395535
↑ Morgenthaler TI, Lee-Chiong T, Alessi C et al Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. Sleep. 2007 Nov;30(11):1445-59. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18041479
↑ Sack RL, Auckley D, Auger RR et al Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine review. Sleep. 2007 Nov;30(11):1484-501. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18041481
↑ Zee PC, Attarian H, Videnovic A. Circadian rhythm abnormalities. Continuum (Minneap Minn). 2013 Feb;19(1 Sleep Disorders):132-47. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23385698 Free PMC Article