thrombin topical (Recothrom)

Indications

• aid in hemostasis during surgical procedures

Dosage

• depends upon indication
• solutions range for 100 units/mL to 2000 units/mL

Adverse effects

anaphylaxis (rare)

Mechanism of action

• conversion of fibrinogen to fibrin
• stimulation of the release reaction
• platelet aggregation

More general terms

• thrombin; coagulation factor IIa
• recombinant protein; chimer
• topical agent