Christensenellaceae

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Introduction

Christensenellaceae allegedly associated with a favorable metebolic profile[2]

Epidemiology

  • relative abundance of Christensenellaceae in the human gut is inversely related to host body mass index (BMI) in different populations
  • related to a healthy status different disease contexts, including obesity & inflammatory bowel disease
  • Christensenellaceae has been associated with human longevity, based on relative abundance of Christensenellaceae is greater in centenarians & supercentenarians in comparison to younger individuals in populations in China[1]
  • relative abundance of Christensenellaceae increases with age[1]

Genetics

  • 30-60% in the relative abundance of Christensenellaceae across individuals is due to genetic factors[1]

More general terms

More specific terms

References

  1. Jump up to: 1.0 1.1 1.2 1.3 Waters JL, Ley RE The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health. BMC Biol 2019. Oct 28 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31660948 PMCID: PMC6819567 Free PMC article. Review.
  2. Jump up to: 2.0 2.1 Brandhorst S, Levine ME, Wei M et al Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nat Commun. 2024 Feb 20;15(1):1309 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38378685 PMCID: PMC10879164 Free PMC article. Clinical Trial https://www.nature.com/articles/s41467-024-45260-9