Christensenellaceae

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Introduction

Christensenellaceae allegedly associated with a favorable metebolic profile[2]

Epidemiology

  • relative abundance of Christensenellaceae in the human gut is inversely related to host body mass index (BMI) in different populations
  • related to a healthy status different disease contexts, including obesity & inflammatory bowel disease
  • Christensenellaceae has been associated with human longevity, based on relative abundance of Christensenellaceae is greater in centenarians & supercentenarians in comparison to younger individuals in populations in China[1]
  • relative abundance of Christensenellaceae increases with age[1]

Genetics

  • 30-60% in the relative abundance of Christensenellaceae across individuals is due to genetic factors[1]

More general terms

More specific terms

References

  1. 1.0 1.1 1.2 1.3 Waters JL, Ley RE The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health. BMC Biol 2019. Oct 28 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31660948 PMCID: PMC6819567 Free PMC article. Review.
  2. 2.0 2.1 Brandhorst S, Levine ME, Wei M et al Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nat Commun. 2024 Feb 20;15(1):1309 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38378685 PMCID: PMC10879164 Free PMC article. Clinical Trial https://www.nature.com/articles/s41467-024-45260-9