intravenous anti-emetic combination

Indications

• relief of nausea/vomiting in palliative care

Dosage

(administration)

• usual rate is 2.7-3.7 mL/hour continuously
• add 60 mL of normal saline to each formula

Formulas* (combinations):

• metoclopramide (Reglan) 40 mg
  • prochlorperazine (Compazine) 30 mg
  • diphenhydramine (Benadryl) 12.5 mg
• chlorpromazine (Thorazine) 25 mg
• droperidol (Inapsine) 5 mg

• metoclopramide (Reglan) 40 mg
  • prochlorperazine (Compazine) 30 mg
  • chlorpromazine (Thorazine) 25 mg
  • droperidol (Inapsine) 5 mg

• metoclopramide (Reglan) 20 mg
  • diphenhydramine (Benadryl) 12.5 mg
  • chlorpromazine (Thorazine) 25 mg
  • droperidol (Inapsine) 5 mg
  • ranitidine (Zantac) 50 mg

• metoclopramide (Reglan) 20 mg
  • diphenhydramine (Benadryl) 100 mg
  • droperidol (Inapsine) 10 mg
  • ranitidine (Zantac) 50 mg

• metoclopramide (Reglan) 30 mg
  • prochlorperazine (Compazine) 30 mg
  • diphenhydramine (Benadryl) 75 mg
  • chlorpromazine (Thorazine) 25 mg
  • droperidol (Inapsine) 3.75 mg

* May add dexamethasone & ranitidine IV every 6 hours

More general terms

• anti-emetic
• pharmacologic combination

Components

• metoclopramide (Reglan, Metozolv ODT)
• prochlorperazine (Compazine, Stemetil, Novamin, Buccastem)
• diphenhydramine (Benadryl, Alledryl, Allergival)
• chlorpromazine (Thorazine, Ormazine, Propaphenin, Sonazine, Chloractil)
• droperidol (Inapsine)
• dexamethasone (Decadron, Maxidex, AK-Dex, Ozurdex)
• ranitidine (Zantac, Gastrosedol)