anti-complement C3d antibody

Clinical significance

Coomb's positive anemia

• anti-IgG & anti-C3d
  • antibodies to glycoprotein antigens
  • systemic lupus erythematosus
• anti-C3d only
  • cold-agglutinin syndrome (Donath-Landsteiner Ab)
  • most drug-related antibodies
  • IgM antibodies
  • IgG antibodies of low affinity
  • activation of complement by immune complexes

Procedure

• direct antiglobulin test

More general terms

• autoantibody