macular ganglion cell complex
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Structure
- the macular ganglion cell complex consists of the retinal nerve fiber layer, ganglion cell layer, & the inner plexiform layer
Pathology
- lower baseline diastolic blood pressure is associated with faster rates of macular ganglion cell comple thinning
- association is more pronounced at higher intraocular pressure levels
Indications
- evaluation of open-angle glaucoma
* more reliable detection of central visual defect than visual field testing
Diagnostic procedures
- optical coherence tomography measures macular ganglion cell complex thickness which correlates with central visual field change in glaucoma
More general terms
Additional terms
- ganglion
- macula retinae, macula lutea, macula, area centralis or punctum luteum
- open-angle glaucoma (OAG)
- optical coherence tomography (OCT)
Component of
References
- ↑ Nishida T, Moghimi S, Mohammadzadeh V et al Association Between Ganglion Cell Complex Thinning and Vision-Related Quality of Life in Glaucoma. JAMA Ophthalmol. 2022;140(8):800-806 PMID: https://www.ncbi.nlm.nih.gov/pubmed/35771529 PMCID: PMC9247856 (available on 2023-06-30) https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2793763
Palmberg PF Making Better-Informed Decisions in Glaucoma JAMA Ophthalmol. 2022;140(8):807-808 PMID: https://www.ncbi.nlm.nih.gov/pubmed/35771536 https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2793764 - ↑ Mohammadzadeh V, Su E, Mohammadi M et al Association of Blood Pressure With Rates of Macular Ganglion Cell Complex Thinning in Patients With Glaucoma. JAMA Ophthalmol. Published online February 9, 2023. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36757702 https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2801301
Tanna AP Blood Pressure and Glaucoma - A Complex Relationship. JAMA Ophthalmol. Published online February 9, 2023 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36757692 https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2801304