BrainComputer Interface Device (IPSIHand)
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Introduction
Indciations:
- stroke rehabilitation[1]
- IPSIHand helps stroke victims regain hand & arm function
- quadriplegia - text messaging
- anarthria & spastic quadriparesis caused by a brainstem stroke (detecting speech)
Mechanism of action
- brain-computer interface robotics
- device consists of an electroencephalography electrode headset that obtains scalp-recorded potentials to identify when a patient intends to move their affected hand, together with a robotic hand brace senses these signals & opens & closes the hand in response
- BrainGate2 clinical trial,
- two intracortical brain-computer interface (BCI) chips the size of a baby aspirin place into part of motor cortex that governs hand movement
- as patient imagined writing, a machine-learning algorithm used signals from individual neurons to recognize patterns produced with each letter
- this allowed patient to communicate in real time with text at a rate of 90 characters per minute[3]
anarthria & spastic quadriparesis caused by a brainstem stroke[4]
- words & sentences decoded directly from cortical activity during attempted speech with use of deep-learning models & a natural-language model
More general terms
References
- ↑ 1.0 1.1 FDA News Release, April 23, 2021 FDA Authorizes Marketing of Device to Facilitate Muscle Rehabilitation in Stroke Patients. https://www.fda.gov/news-events/press-announcements/fda-authorizes-marketing-device-facilitate-muscle-rehabilitation-stroke-patients
- ↑ Neurolutions IPSHI Hang: Harness the powerof the mind. https://www.neurolutions.com/device
- ↑ 3.0 3.1 George J Implanted Sensor Translates Brain Signals Into Text. Brain-computer interface decodes handwriting movements from neural activity. MedPage Today May 12, 2021 https://www.medpagetoday.com/neurology/generalneurology/92545
Willet FR, Avansino DT, Hockberg LR et al High-performance brain-to-text communication via handwriting. Nature 2021 593(7858):249-254. May 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33981047 https://www.nature.com/articles/s41586-021-03506-2
Rajeswaran P, Orsborn AL Neural interface translates thoughts into type. Nature 2021. 593(7858):197-198. May 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33981045 https://www.nature.com/articles/d41586-021-00776-8
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2). ClinicalTrials.gov https://www.clinicaltrials.gov/ct2/show/NCT00912041 - ↑ 4.0 4.1 Moses DA, Metzger SL, Liu JR Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria. N Engl J Med 2021; 385:217-227 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34260835 https://www.nejm.org/doi/full/10.1056/NEJMoa2027540