quadriplegia
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Introduction
Paralysis of all 4 extremities (i.e. both arms & legs) to a similar degree.
Clinical trials
- brain-computer interface research offers promise[3]
- BrainGate2 clinical trial,
- two intracortical brain-computer interface (BCI) chips the size of a baby aspirin place into part of motor cortex that governs hand movement
- as patient imagined writing, a machine-learning algorithm used signals from individual neurons to recognize patterns produced with each letter
- this allowed patient to communicate in real time with text at a rate of 90 characters per minute[4]
More general terms
Additional terms
References
- ↑ Stedman's Medical Dictionary 26th ed, Williams & Wilkins, Baltimore, 1995
- ↑ The Merck Manual, 14th ed, Merck, Sharp & Dohme, Rathway, NJ, 1982
- ↑ 3.0 3.1 Hochberg LR et al, Neuronal ensemble control of prosthetic devices by a human with tetraplegia. Nature 2006, 442:164 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16838014
- ↑ 4.0 4.1 George J Implanted Sensor Translates Brain Signals Into Text. Brain-computer interface decodes handwriting movements from neural activity. MedPage Today May 12, 2021 https://www.medpagetoday.com/neurology/generalneurology/92545
Willet FR, Avansino DT, Hockberg LR et al High-performance brain-to-text communication via handwriting. Nature 2021 593(7858):249-254. May 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33981047 https://www.nature.com/articles/s41586-021-03506-2
Rajeswaran P, Orsborn AL Neural interface translates thoughts into type. Nature 2021. 593(7858):197-198. May 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33981045 https://www.nature.com/articles/d41586-021-00776-8
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2). ClinicalTrials.gov https://www.clinicaltrials.gov/ct2/show/NCT00912041