phytosterol

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Introduction

One of the 4 classes of phytoestrogens. Derived from vegetable oil & certain fruits & vegetables. They are absorbed in proportion to absorbed cholesterol, but to a much lesser extent (0.1%). Phytosterols inhibit intestinal cholesterol absorption. This, in turn, stimulates hepatic cholesterol biosynthesis. The net effect is a lowering of total cholesterol & LDL cholesterol. 2g/day can lower LDL cholesterol by 5%.[3]

Phytosterols include:

Phytosterols may be found in black-eyed peas, tea, lettuce

More general terms

More specific terms

Component of

References

  1. Schabath MB et al. Dietary phytoestrogens and risk of lung cancer JAMA 2005 Sep 28;294(12):1493-504 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16189362
  2. Miettinen TA, Railo M, Lepantalo M, Gylling H. Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endarterectomy. J Am Coll Cardiol. 2005 Jun 7;45(11):1794-801. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15936608
  3. 3.0 3.1 Prescriber's Letter 15(9): 2008 Supplements for Lowering Cholesterol: an Update Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240909&pb=PRL (subscription needed) http://www.prescribersletter.com