benoxinate; oxybuprocaine; oxybucaine; oxibuprokain; oxyriprocaine; benoxil

Indications

• local anesthetic used in ophthalmology & otolaryngology

Mechanism of action

• binds to sodium channel
• reversibly stabilizes & decreases permeability of neuronal membrane to sodium ions
• repolarization of the neuronal membrane is inhibited thus blocking initiation & conduction of nerve impulses

More general terms

• local anesthetic

Component of

• benoxinate/fluorescein

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4633
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6420040