magnesium gluconate (Magonate)

Introduction

Tradename: Magonate.

Indications

treatment of magnesium deficiency

Contraindications

pregnancy-category :value A

safety-in-lactation :value +

Dosage

• 27-54 mg BID-TID
• 100 mg QID
• dosage adjustment &/or monitoring necessary in patients with renal failure

Pharmacokinetics

• 15 to 30% absorbed following oral administration
• elimination :route kidney)

Adverse effects

• diarrhea
• hypotension
• abdominal cramps
• muscle weakness
• respiratory depression

Drug interactions

• may increase effects of non-depolarizing neuromuscular junction blockers

Mechanism of action

cofactor in enzymatic reactions

More general terms

• pharmaceutical magnesium

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=19261