bryostatin

Indications

• investigational agent for treatment of Alzheimer's disease

Dosage

• 20 ug IV

Mechanism of action

• modulates protein kinase C-epsilon
• effects on neurons
• enhances synaptogenesis
• inhibits apoptosis
• reduces formation of beta-amyloid
• inhibits phosporylation of tau

Notes

• isolated from the marine bryozoan Bugula neritina

More general terms

• neurologic agent