ingenol disoxate
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Introduction
diterpene ester extracted & purified from the plant Euphorbia peplus
Indications
Contraindications
- do not use near lips or eyes
Dosage
- applied on 2-3 consecutive days to large areas of the face, chest, & scalp
- developed for application to areas ranging up to 250 cm2[1]
- use ingenol mebutate for areas < 25 cm2
Adverse effects
- see ingenol mebutate
Mechanism of action
- localized induction of necrosis followed by a transient inflammatory response
More general terms
Additional terms
References
- ↑ 1.0 1.1 Bankhead C American Academy of Dermatology (AAD) 2017 Meeting Coverage Brief, Broad-Area Treatment Clears Actinic Keratosis
High patient satisfaction with ingenol disoxate https://www.medpagetoday.com/Dermatology/SkinCancer/63706 - ↑ Siegel DM et al. Safety and efficacy of ingenol disoxate 3-day field treatment of actinic keratoses on face, chest, or balding scalp. American Academy of Dermatology (AAD) 2017. Poster 4364.
- ↑ Berman B, et al High patient satisfaction and improved cosmetic outcomes after a 3-day field treatment of actinic keratosis with ingenol disoxate on the fact, chest, and balding scalp. American Academy of Dermatology (AAD) 2017. Poster 4358