carbapenemase
Jump to navigation
Jump to search
Epidemiology
Pathology
- carbapenem-resistant Enterobacteriaceae
- mobility of the blaKPC* gene
- spread by the Tn4401 transposon that carries the gene or by the plasmids that harbor the transposon
- intraindividual or interindividual nonclonal dissemination
* KPC = Klebsiella pneumoniae carbapenemase
Pharmacology
- bacterial enzymes with ability to hydrolyze penicillins, cephalosporins, monobactams, & carbapenems
Laboratory
More general terms
References
- ↑ Queenan AM, Bush K Carbapenemases: the Versatile beta-Lactamases. Clin Microbiol Rev. 2007 Jul; 20(3): 440-458. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/17630334 Free PMC Article <Internet> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1932750/
- ↑ Mulvey MR, Haraoui LP, Longtin Y Multiple Variants of Klebsiella pneumoniae Producing Carbapenemase in One Patient. N Engl J Med 2016; 375:2408-2410. December 15, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27974041 Free full text <Internet> http://www.nejm.org/doi/full/10.1056/NEJMc1511360
- ↑ 3.0 3.1 Woodworth KR, Walters MS, Weiner LM, et al. Vital Signs: Containment of Novel Multidrug-Resistant Organisms and Resistance Mechanisms - United States, 2006-2017. MMWR Morb Mortal Wkly Rep. ePub: 3 April 2018. https://www.cdc.gov/mmwr/volumes/67/wr/mm6713e1.htm