IFNL3 (IL28B) variation rs12979860

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^[1]

Indications

hepatitis C genotype 1 infection

Clinical significance

IFNL3 (IL28B) variation (rs12979860) is the strongest baseline predictor of response to PEG-interferon-alpha- containing regimens in HCV genotype 1 patients^[1]

More general terms

gene mutation testing; gene mutation analysis

References

↑ ^1.0 ^1.1 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline information for boceprevir, peginterferon alfa-2a, peginterferon alfa-2b, ribavirin, telaprevir and IFNL3. https://www.pharmgkb.org/guideline/PA166110235

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