peginterferon

Introduction

Attachment of a polyethylene glycol moeity to interferon-2 alpha or interferon-2 beta results in a longer half-life of the protein.

Contraindications

• avoid in patients with depression

Laboratory

• IFNL3 variation rs12979860 predicts response to PEG-interferon-alpha

More general terms

• chemically-modified protein
• pharmaceutical interferon

More specific terms

• peginterferon alfa 2a (Pegasys)
• peginterferon alfa 2b (Pegintron)