intrinsic factor antibody (INTRINS) in serum
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Indications
- gastritis
- pernicious anemia (50%)*
- hyperthyroidism (3-6%)
- insulin-dependent diabetes mellitus (3-6%)
* tesing for intrinsic factor Ab in the diagnosis of pernicious anemia not indicated[3]
Specimen
- serum or plasma (EDTA)
- avoid administration of vitamin B12 48 hours prior to drawing sample.
- stable 4 hours at room temperature of 3 days refrigerated.
- freeze at -20 degrees C for longer storage.
Interferences
- false positives:
- increased cyanocobalamin
More general terms
More specific terms
Additional terms
- anti-intrinsic factor antibody (INTRINS)
- intrinsic factor; gastric intrinsic factor; IF; INF (GIF, IFMH)
- pernicious anemia
References
- ↑ Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
- ↑ Intrinsic Factor Blocking Antibody Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0070210.jsp
- ↑ 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 16, American College of Physicians, Philadelphia 2012