conidiobolomycosis

Etiology

• Conidiobolus coronatus
• Conidiobolus incongruus
• Conidiobolus lamprauges

Epidemiology

• rare
• predominately affects middle age men in tropical countries
• due to infection with saprophytic fungus that can survive in soil & dried vegetables for long periods of time

Pathology

• affects upper respiratory mucosa & adjacent subcutaneous tissues
• infection probably results from inhalation of fungal pathogens or from trauma.

Microscopic pathology

• granulomatous inflammation & fungal elements surrounded by eosinophilic material

Clinical manifestations

• mycosis of nose & paranasal sinuses
• erythema, edema, & tenderness over the nasal dorsum & forehead, extending to the soft tissue around both eyes (case report)
• case of disseminiated conidiobolomycosis caused by Conidiobolus lamprauges in a patient with malignant lymphoma

Laboratory

• skin biopsy

Management

• itraconazole, trimethoprim-sulfamethoxazole & 10% potassium iodide for 6 months (case report)

More general terms

• entomophthoramycosis

Additional terms

• Conidiobolus