Heerfordt-Waldenstrom syndrome; uveoparotid fever

Etiology

• may be initial presentation of sarcoidosis

Pathology

• parotid gland biopsy (image) no necessary
  • scattered granulomas with focal central necrosis
  • stains for acid-fast bacilli & fungi negative
  • histopathology image (parotid)
• compression of facial nerve results in facial nerve palsy

Clinical manifestations

• anterior uveitis
• parotiditis
• fever
• with or without facial nerve palsy
  • can result in sicca symptoms
• images

Diagnostic procedures

• tissue biopsy not indicated

Radiology

• chest radiograph
  • bilateral hilar adenopathy
  • paratracheal adenopathy may be noted
• CT of the head

Differential diagnosis

• Sjogren syndrome

Management

• glucocorticoid
  • prednisone 60 mg QD (case report)
  • enlargement with uniform contrast enhancement of parotids

More general terms

• syndrome