Heerfordt-Waldenstrom syndrome; uveoparotid fever
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Etiology
- may be initial presentation of sarcoidosis[2]
Pathology
- parotid gland biopsy (image) no necessary
- scattered granulomas with focal central necrosis
- stains for acid-fast bacilli & fungi negative
- histopathology image (parotid)[3]
- compression of facial nerve results in facial nerve palsy
Clinical manifestations
- anterior uveitis
- parotiditis
- fever
- with or without facial nerve palsy
- can result in sicca symptoms[1]
- images[3]
Diagnostic procedures
- tissue biopsy not indicated
Radiology
- chest radiograph
- bilateral hilar adenopathy
- paratracheal adenopathy may be noted
- CT of the head
Differential diagnosis
Management
- glucocorticoid
- prednisone 60 mg QD (case report)[3]
- enlargement with uniform contrast enhancement of parotids
More general terms
References
- ↑ Jump up to: 1.0 1.1 Medical Knowledge Self Assessment Program (MKSAP) 17, 18, 19. American College of Physicians, Philadelphia 2015, 2018, 2022.
- ↑ Jump up to: 2.0 2.1 Denny MC, Fotino AD. The Heerfordt-Waldenstrom syndrome as an initial presentation of sarcoidosis. Proc (Bayl Univ Med Cent). 2013 Oct;26(4):390-2. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24082416 Free PMC Article
- ↑ Jump up to: 3.0 3.1 3.2 3.3 Dua A, Manadan A (images) Images in Clinical Medicine. Heerfordt's Syndrome, or Uveoparotid Fever. N Engl J Med 2013; 369:458. August 1, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23902485 Free full text <Internet> http://www.nejm.org/doi/full/10.1056/NEJMicm1303454
- ↑ Weerakkody Y, Gaillard F Heerfordt syndrome http://radiopaedia.org/articles/heerfordt-syndrome