[60]fullerene; buckminsterfullerene; buckyball
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Structure
- nanoparticle characterized by a spherical geometry & hollow interior
- comprised of 60 carbon atoms
- it appears all of the are sp2 hybridized
Pharmacokinetics
- completely eliminated from the blood in 4 days[1]
- mainly biliary elimination
- enterohepatic circulation may play some role
Comparative biology
- olive oil/fullerene-60 gavage increased mean lifespan of rats from 30 months to 62 months; olive oil alone increased mean lifespan to 41 months
- olive oil/]fullerene-60 gavage increased maximum lifespan from 38 months to 66 months; olive oil alone increased maximum lifespan to 58 months
More general terms
References
- ↑ 1.0 1.1 Baati T, Bourasset F, Gharbi N et al The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene. Biomaterials. 2012 Jun;33(19):4936-46. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22498298
- ↑ Wikipedia: Fullerene https://en.wikipedia.org/wiki/Fullerene