transcription factor Sp2; stimulatory protein 2 (Sp2, KIAA0048)

Function

• binds to GC box promoters elements & selectively
• activates mRNA synthesis from genes that contain functional recognition sites

Structure

• belongs to the Sp1 C2H2-type Zn+2-finger protein family
• contains 3 C2H2-type Zn+2 fingers

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• Sp1 transcription factor family
• C2H2 type zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6668
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6668
• OMIM: https://mirror.omim.org/entry/601801
• UniProt: http://www.uniprot.org/uniprot/Q02086.html