cobimetinib
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Indications
- metastatic melanoma
- BRAF V600E or BRAF V600K gene mutation-positive
- craniopharyngioma[2]
- for use in combination with vemurafenib[1]
Mechanism of action
- inhibits MEK
Notes
More general terms
References
- ↑ 1.0 1.1 1.2 Mescape Oncology. Sept 30, 2014 New Standard in Melanoma: Combo of BRAF and MEK Inhibitors. http://www.medscape.com/viewarticle/832566?nlid=66983_2202
- ↑ 2.0 2.1 ClinicalTrials.gov Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma. https://clinicaltrials.gov/study/NCT03224767