isavuconazonium sulfate (Cresemba)

Indications

• invasive aspergillosis
• invasive mucormycosis

Dosage

• oral or intravenous administration

Adverse effects

• nausea, vomiting
• constipation, diarrhea
• headache
• hepatotoxicity, abnormal liver function tests
• hypokalemia
• dyspnea
• cough
• peripheral edema
• infusion reactions
• severe allergic reactions
• Stevens-Johnson syndrome, toxic epidermal necrolysis or other severe skin reaction

Mechanism of action

• azole that targets fungal cell wall

More general terms

• antifungal agent
• pyrrole
• aromatic compound
• nitrile
• ester
• carbamate

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=72196309